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285 results
  • Hormone release from a kidney cell, STORM and TIRFM
  • Raynaud's Phenomenon
  • Solanum laciniatum Aiton Solanaceae. Kangaroo Apple. Evergreen shrub. Distribution: New Zealand and the east coast of Australia. It contains steroidal saponins that can be converted into steroids, including progesterone, oestrogens, cortisone, prednisolone etc. In 1943, Professor Russell Marker discovered a method of obtaining an unsaturated steroidal saponine, diosogenin, from Mexican yam (Dioscorea mexicana), which can easily and cheaply be converted into steroids, such as prednisone and progesterone, reducing the price of steroid production to a fraction (0.5%) of its former cost. For 20 years drug companies showed little interest, and it was only as a result of Professor Marker forming his own company, and the concerted efforts of several gynaecologists, physiologists and birth-control advocates, that the contraceptive pill was ‘born’ in 1960. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Human skin section, histology
  • Dahlia merckii
  • Pulsatilla vulgaris Mill. Ranunculaceae Distribution: Europe. Lindley (1838) and Woodville (1790) knew this as Anemone pulsatilla, the common name being Pasque (Easter) Flower. At the end of the 18th century it was recommended for blindness, cataracts, syphilis, strokes and much more, treatments which, as was clear to physicians at the time, were valueless. Gerard (1633) writes: ‘They serve only for the adorning of gardens and garlands, being floures of great beauty’. It is in the buttercup family, Ranunculaceae, all members of which are poisonous. It was recommended, by mouth, for ‘obstinate case of taenia’ (tapeworms). One hopes it was more toxic to the worm than the patient. Flowers with a central disc and radiating florets were regarded as being good for eye complaints under the Doctrine of Signatures. Porta (1588) writes (translated): ‘Argemone [Papaver argemone], and anemone, have flowers of this shape, from this they cure ulcers and cloudiness of the cornea’. There were occupational diseases even before there were words like pneumoconiosis, and Lindley writes that ‘the powder of the root causes itching of the eyes, colic and vomiting, if in pulverising it the operator do not avoid the fine dust which is driven up.’ Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Cynoglossum officinale L. Boraginaceae. Houndstongue. Distribution: Europe. Culpeper (1650) writes: “... being roasted and laid to the fundament, helps the haemorrhoids. It is also good against burnings and scaldings.” It contains hepatocarcinogenic pyrrolizidine alkaloids and while people are known to eat the young leaves as a vegetable, this is inadvisable. The whole plant is hairy and may cause contact dermatitis. The use of herbal remedies, which contain these alkaloids, by the Bantu of southern Africa correlates with their high incidence of tumours of the liver and pancreas. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Teucrium marum L. Lamiaceae Cat Thyme Distribution: Europe. Teucrium is named after Teucer (who lived in the era between 1400 and 1000 BC) the first King of Troy. Dioscorides named a medicinal herb after Teucer, and Linnaeus consolidated this in 1753. Assume property is the same as Germander, Teucrium chamaedrys. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Raynaud's Phenomenon
  • Crocus vernus (L,)Hill Iridaceae. and Bombus terrestris, spring crocus with bumble bee. Distribution: Europe. Crocus sativus is the source of Saffron, a spice from the pollinia of the flower
  • HeLa cells, immortal human epithelial cancer cell line, SEM
  • Cistus incanus ssp creticus Juss. Cistaceae. Rock Rose. Distribution: Crete. Interesting symbiosis with fungus called Tuber melanosporum which increases nutrient absorption for the plant and inhibits growth of other plants in the vicinity. It is a source of the resin ‘labdanum’ (a.k.a. ‘ladanum’) used in perfumes (similar smell to ambergris), as is Cistus ladanifer. It has no medical uses now, and such use was dwindling even in the 18th century. In the 16th century (Henry Lyte’s 1575 translation of Rembert Dodoen’s Cruydeboeck of 1554) its uses were described (directly copied from Dioscorides’ Materia Medica (70AD)) as: ‘Ladanum dronketh with olde wine, stoppeth the laske [periods], and provoketh urine. It is very good against the hardness of the matrix or mother [uterus] layde to in the manner of a pessarie, and it draweth down the secondes or afterbirth, when it is layde upon quicke coles [hot coals], and the fumigation or parfume thereof be received up into the body of women. // The same applied to the head with Myrrhe and oyle of Myrrhe, cureth the scurffe, called Alopecia, and keepeth the heare [hair] from falling of [sic], but whereas it is already fallen away, it will not cause the heare to growe agayne. // ...' and goes on in this vein about its uses for pain in the ears, and removing sores and scars and other things. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Thermogram of an infected middle finger, left hand.
  • HIV transcription, HIV viral life cycle, illustration
  • Healthy human adult brain viewed from the side, tractography
  • HeLa cells, immortal human epithelial cancer cell line, SEM
  • Woodlouse, SEM
  • HIV integration, HIV viral life cycle, illustration
  • Apoptosis
  • Camassia leichtlinii (Baker)S.Watson Hyacinthaceae. Great Camas, Quamash. The species was named for Maximillian Leichtlin (1831-1910 of Baden , Germany, bulb enthusiast who corresponded with J.G. Baker at Kew. Bulbous herb. Distribution: North America. The bulbs of Camassia species were eaten by the Native Americans, the Nez Perce, after cooking by steaming for a day - which suggests they may be poisonous raw. They gave them to the American explorers, Meriwether Lewis and William Clerk, on their expedition (1804-1806) when they ran out of food. The bulbs of the similar looking 'Death camus', Toxicoscordion venenosum have been fatal when ingested by mistake (RBG Kew on-line). Steroidal saponins, which are precursors in the manufacture of steroids and cytotoxic activity has been detected in the sap of the bulbs. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Purple bacteria or purple photosynthetic bacteria are pigmented by bacteriochlorophyll and carotenoids, giving them a colourful range of purples, pinks and oranges. They photosynthesize without producing oxygen as a by-product. This type of bacteria are proteobacteria which are phototrophic (produce their own food via photosynthesis)
  • Prostate cancer cells treated with nano sized drug carriers
  • Head louse clinging to strand of human hair, SEM
  • Myxoid liposarcoma, microscopy
  • HeLa cell, immortal human epithelial cancer cell line, SEM
  • Cynara cardunculus L. Asteraceae. Cardoon, Globe Artichoke, Artechokes, Scolymos cinara, Cynara, Cinara. Distribution: Southern Europe and North Africa. Lyte (1576) writes that Dodoens (1552) could find no medical use for them and Galen (c.200 AD) said they were indigestible unless cooked. However, he relates that other authors recommend that if the flower heads are soaked in strong wine, they 'provoke urine and stir up lust in the body.' More prosaically, the roots boiled in wine and drunk it cause the urine to be 'stinking' and so cures smelly armpits. He adds that it strengthens the stomach so causing women to conceive Male children. He goes on to say that the young shoots boiled in broth also stir up lust in men and women, and more besides. Lyte (1576) was translating, I think with elaborations, from the chapter on Scolymos cinara, Artichaut, in Dodoen's Croydeboeck (1552) as L'Ecluse's French translation, Dodoens Histoire des Plantes (1575) does not mention these latter uses, but Dodoen's own Latin translation, the Pemptades (1583), and Gerard's Herbal (1633) both do so. It is useful in understanding the history of these translations to realise that Gerard uses, almost verbatim, the translation of the 'smelly armpit' paragraph from Lyte. Photographed in the Medicinal Garden of the Royal College of Physicians, London.
  • Human brain cancer stem cells treated with graphene, SEM
  • Raynaud's Phenomenon
  • Lung cancer cells grown in culture, SEM
  • Mouse brain capillaries, SEM